2 February Adams Named Fraternal Order of Eagles Diabetes Research Chair February 2, 2017 By The Fraternal Order of Eagles Diabetes Research Center 0 Christopher Adams, MD, PhD, has been named the Fraternal Order of Eagles Diabetes Research Chair. This position has been endowed by the Fraternal Order of Eagles (FOE) to propel and accelerate the pace of discoveries in the FOE Diabetes Research Center (FOEDRC), whose mission is to advance knowledge of the mechanisms of diabetes and its related complications through cutting-edge research. Dr. Adams is a Professor of Internal Medicine and of Molecular Physiology and Biophysics at the University of Iowa. He has primarily focused on investigating the problem of skeletal muscle atrophy and its relationship with type 2 diabetes. He and his lab have identified several previously unrecognized molecular mechanisms that lead to skeletal muscle atrophy and has identified proteins that when activated could maintain healthy muscle or prevent muscle loss. His current investigations, which seek to understand the regulation and function of these pathways, may lead to novel approaches to combating muscle weakness resulting from aging and disuse. Dr. Adams has developed a novel systems-based strategy for identifying molecules that improve muscle mass and function, including several promising compounds with strong potential for pharmaceutical development. The discoveries and advances from his laboratory led Dr. Adams to form a UI-based biotechnology company called Emmyon, Inc., which is forging strategic partnerships to advance its missions. Through Emmyon, Dr. Adams hopes to generate beneficial products for human and animal health, as well as other future avenues for research and development. Dr. Adams’s national reputation has been on a rapidly increasing trajectory, not only with publications in leading scientific journals, but also with widespread coverage of his laboratory’s discoveries appearing in The Wall Street Journal, US News and World Report, ABC News, and NBC News, among many other outlets. In addition to his extensive and widely recognized research activities as a basic and translational scientist, Dr. Adams practices endocrinology primarily at the Iowa City VA and contributes to the training of medical students, residents, fellows, with particular focus on developing the next generation of biomedical scientists. I consider him to be one of the most talented physician scientists within the Department of Internal Medicine. He knows how to recognize novel, important scientific questions and how to assemble the talent and innovative approaches to answer them. This chair will enable him to attract other talented investigators to the University of Iowa. 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Ling Yang, Rajan Sah and Adam Rauckhorst are summarized below. Iowa Leadership welcome the Fraternal Order of Eagles Board of Trustees On Monday, August 15, the University of Iowa Foundation (UIF) welcomed the Fraternal Order of Eagles (FOE) Board of Directors to the University of Iowa for their annual visit to the FOEDRC. DRC Researcher Chris Adams Develops New Therapy for Age-Related Muscle Atrophy Scientists at the FOE Diabetes Research Center and University of Iowa have discovered the first example of a protein that causes muscle weakness and loss during aging. The protein, ATF4, is a transcription factor that alters gene expression in skeletal muscle, causing reduction of muscle protein synthesis, strength, and mass. The UI study also identifies two natural compounds, one found in apples and one found in green tomatoes, which reduce ATF4 activity in aged skeletal muscle. DRC Researchers Publish Major Breakthrough In Understanding How Diabetes Induces Eye Damage In the retina, diabetes damages nerves before it damages blood vessels. Diabetes is a major risk factor for severe vision loss and blindness. A condition known as retinal diabetic neuropathy causes visual impairment through the degeneration of small nerves (neurons) in light-sensitive tissue called the retina, which lines the back of the eye. Showing 0 Comment Comments are closed.