12 October An M-Health Intervention To Increase Activity Among Patients At Risk For Type 2 Diabetes October 12, 2016 By The Fraternal Order of Eagles Diabetes Research Center 0 In 2013, Dr. Philip Polgreen was the recipient of a FOEDRC Pilot Grant for his research entitled, “To evaluate a novel tool using text messages as a mechanism to promote sustained weight loss in patients with obesity and insulin resistance.” This cutting edge science was recently recognized and awarded additional funding by the National Institutes of Health (NIH). Exercise and weight loss have many health benefits. In fact, increasing activity levels and subsequent weight loss can induce remission of type II diabetes. However it is incredibly difficult for patients to consistently exercise enough to lose weight. Most guidelines recommend that diabetics increase activity, but there are currently few ways for a physician to determine if indeed patients are following such advice after clinic visits. Furthermore, exactly how to effectively encourage activity and weight loss in a cost effective manner is not clear. However, what is clear is that a sedentary lifestyle is not only a risk factor for type two diabetes (T2D), but it can also exacerbate the disease. Recommending increased physical activity is therefore a cornerstone of T2D prevention and management. Historically, increasing activity was synonymous with exercise; however, even much more modest activity levels (e.g. simply walking) or merely decreasing the proportion of sedentary time may be sufficient to improve health outcomes. Some interventions designed to increase activity have shown promise; others have been less successful. The availability of inexpensive pedometers, and more recently, low-cost triaxial accelerometers, has now made it much easier to monitor activity levels and provide feedback to users. These devices are ideal for capturing activity associated with walking, the most popular and acceptable form of exercise for patients with T2D, but only if patients actually wear them. Thus, there is a need to develop pragmatic approaches that encourage patients to not only wear these monitoring devices, but also to motivate them to increase their activity. Because it has been difficult to generalize and maintain exercise programs for people with pre-diabetes or T2D, Dr. Polgreen’s interdisciplinary research group created MapTrek, a mobile-phone-based walking game that allows people to take a virtual walk in any number of interesting locations around the world and track their progress against the progress of other people like themselves on an interactive map. Steps are counted using a commercially-available triaxial accelerometer (e.g., a Fitbit), and patients see their own updated progress overlaid on Google Maps, with all the usual Google Maps features (e.g., zooming, street view, etc.) available. The objective is to alert patients at risk for or diagnosed with T2D of their activity levels in the innovative game-based environment, thereby encouraging them, first to walk more every day and, second, to maintain these new increased levels of physical activity. Dr. Polgreen’s game will also focus on motivating patients to increase their walking pace and reduce their sedentary time. This R21 grant from the NIH, will fund a pilot clinical trial to test the effectiveness of their game against the effectiveness of Fitbits alone. Congratulations to Dr. Polgreen’s team on this award to enable our patients to have fun while losing weight and preventing diabetes! Related Articles Technology Developed By DRC Researcher Could Preserve Vision for Diabetes Patients University of Iowa Health Care patients are the first in the nation to have access to a new technology that uses artificial intelligence (AI) to diagnose diabetic retinopathy. The technology, known as IDx-DR, is the only medical device authorized by the Food and Drug Administration that uses AI for the autonomous detection of diabetic retinopathy. The device’s algorithm makes the diagnosis based on imaging of the patient’s retina without the need for an eye specialist to interpret the results. New Ways To Predict The Risk Of Gestational Diabetes DRC Director's Report - November 2017 We are pleased to announce that Dr. Wei Bao, Assistant Professor in the Department of Epidemiology, College of Public Health, University of Iowa, and a member of the Fraternal Order of Eagles Diabetes Research Center (FOEDRC) was recently awarded a $419,000 grant from the National Institutes of Health to fund a project entitled: Pregnancy-associated microRNAs in plasma as predictors of gestational diabetes. Some of the preliminary work that contributed to this award were provided by pilot funding from the FOEDRC. Chemicals in Plastic Bottles and the Risk of Obesity and Diabetes DRC Director's Report, August 2017 As you all know, there are many factors that may contribute to the growing risk of obesity and diabetes worldwide. Many understand that an unhealthy diet, gaining too much weight or not exercising enough will certainly contribute to increasing your risk of diabetes. However, there is also a growing realization that certain environmental exposures and chemicals to which we might be exposed could also increase this risk. Stressing Muscle Metabolism Prevents Obesity and Type 2 Diabetes Exciting new research was recently published in the EMBO Journal by the laboratory of FOEDRC Director, Dale Abel. The study suggests that gently stressing muscle metabolism could help prevent obesity and type 2 diabetes. The study was carried out on mice where the team found triggering a type of metabolic stress increased levels of a hormone called fibroblast growth factor-21 (FGF21). The findings showed the animals were completely protected from obesity and diabetes. Interestingly, in the mice which had already started to develop the condition, the hormone reversed the diabetes and helped them return to a normal weight with normal blood sugar levels. How Diabetes Harms The Heart Study in mice involving FOEDRC researchers, reveals heart-damaging pathway triggered by insulin, identifies possible drug targets to prevent or treat heart failure. Diabetes is hard on the heart. Cardiovascular disease is the leading cause of death in people with diabetes, and risk for heart failure—where the heart can’t pump enough blood—is two to three times higher in men and up to five times higher in women with diabetes compared to people without diabetes. DRC Researchers Publish Major Breakthrough In Understanding How Diabetes Induces Eye Damage In the retina, diabetes damages nerves before it damages blood vessels. Diabetes is a major risk factor for severe vision loss and blindness. A condition known as retinal diabetic neuropathy causes visual impairment through the degeneration of small nerves (neurons) in light-sensitive tissue called the retina, which lines the back of the eye. Showing 0 Comment Comments are closed.