6 December The University of Iowa and FOE DRC Welcome Dr. Ethan Anderson December 6, 2016 By The Fraternal Order of Eagles Diabetes Research Center 0 I am pleased to announce the recruitment of Ethan Anderson, PhD to the FOEDRC. Dr. Anderson recently joined the Division of Pharmaceutics and Translational Therapeutics within the Department of Pharmaceutical Sciences and Experimental Therapeutics as an Associate Professor in the University of Iowa College of Pharmacy. Dr. Anderson received his B.S. from the University of Minnesota and PhD from Yale University. Dr. Anderson’s research is focused on cardiac complications of diabetes, cardiac inflammation and fibrosis, and towards development of novel therapeutics and biomarkers of heart disease risk. The primary research focus of Dr. Anderson’s laboratory is centered on the role of lipids and reactive oxygen species (ROS) in altering mitochondrial function, and in how the mitochondria uses these and other molecular intermediates to communicate with the rest of the cell, particularly the nucleus, in normal physiological states as well as disease. An increased understanding of these processes, coupled with improvements in mitochondrial-targeted pharmaceutical chemistry, will allow a new era to become realized where mitochondria are a viable therapeutic target in disease management. Dr. Anderson’s team recently established a strong and dynamic collaboration with cardiac surgeons at East Carolina Heart Institute (ECHI), and this has allowed them to obtain human cardiac tissue biopsies from patients at time of surgery. Using a number of techniques to study mitochondrial function at the subcellular (i.e. organelle) and whole cell level in human heart tissue, they have recently uncovered a number of interesting mitochondrial abnormalities present in patients with type 2 diabetes. Anderson’s group was one of the first to show the existence of mitochondrial dysfunction in heart samples obtained from humans with diabetes in a landmark publication in the Journal of the American College of Cardiology in 2009. Dr. Anderson’s current research projects span clinical, translational and basic science research. His approach increases the likelihood of developing therapeutic strategies that will be able to enter human trials. Research in the Anderson lab is supported by Grants from the National Institutes of Health and the pharmaceutic industry. Related Articles Iowa Leadership welcome the Fraternal Order of Eagles Board of Trustees On Monday, August 15, the University of Iowa Foundation (UIF) welcomed the Fraternal Order of Eagles (FOE) Board of Directors to the University of Iowa for their annual visit to the FOEDRC. Iowa Names Dr. Abel Chair and DEO of Department of Internal Medicine IOWA CITY, IA - E. Dale Abel, MD, PhD, has been appointed the new Chair and Departmental Executive Officer of the University of Iowa Roy J. and Lucille A. Carver College of Medicine Department of Internal Medicine, effective Jan. 1, 2016. Eagles, Iowa Formalize Bridge To The Cure Project On Tuesday, October 30, The Fraternal Order of Eagles (F.O.E.) Board of Grand Trustees met with leadership from the University of Iowa to formalize the F.O.E.'s Bridge to the Cure project, which aims to translate research projects at the F.O.E. Diabetes Research Center into new medications to help alleviate the effects of diabetes. With the new agreement, the F.O.E. Diabetes Research Center staff, led by Director Dr. E. Dale Abel, will form a committee, including one Eagles member, to recommend research projects for trial drug testing. Once a recommendation is made, it will be passed along to the F.O.E.'s Board of Grand Trustees, who will determine whether or not to issue a grant from the F.O.E. Diabetes Research Center Fund to facilitate the trials. Iowa State Eagles & SoldierStrong Partner to Donate Ekso GT Suit to Younker Rehabilitation DES MOINES, Iowa. - The Iowa State Fraternal Order of Eagles have partnered with SoldierStrong, a nonprofit organization dedicated to providing advanced medical technologies to veterans, to donate an EksoGT™ exoskeleton to Younker Rehabilitation at Iowa Methodist Medical Center. The robotic exoskeleton is used in rehabilitation to help people—including veterans—who have had a stroke or spinal cord injury walk again. DRC Director's Update - August 2019 FOE Diabetes Research Center faculty recognize the importance of continuing the tradition of research excellence as we fight for the bridge to the cure. Because of this, part of our mission must be the preparation of the next generation of diabetes researchers. In addition to our commitment to training Ph.D. students and Postdoctoral scholars, the FOEDRC is a leader at the University of Iowa in providing research experience to our undergraduate students. How Diabetes Harms The Heart Study in mice involving FOEDRC researchers, reveals heart-damaging pathway triggered by insulin, identifies possible drug targets to prevent or treat heart failure. Diabetes is hard on the heart. Cardiovascular disease is the leading cause of death in people with diabetes, and risk for heart failure—where the heart can’t pump enough blood—is two to three times higher in men and up to five times higher in women with diabetes compared to people without diabetes. 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